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Protocols: Picamilion (nicotinyl-y-aminobutyric acid)

Psychoactive

Description: Picamilon was first synthesized in 1970. It is a white crystalline power that is odorless, highly hygroscopic and readily soluble in water. It is a combination of niacin and GABA in the same molecule, which increases to potency of each component.

Method of Action: Affects cerebral circulation and neural regulation in similar manner to gamma aminobutyric acid (GABA). Anti-edematous action of Picamilon is linked with a change in energy metabolism in neurologic tissue.

Indications and Usage: Normal dosage (.01 to .05 grams). Acts on cerebral circulation and neural regulation to create tranquilizing effect, restore balance between sympathetic and parasympathetic nervous systems, reduce the emotional effects of life stress and inhibit anxiety and aggression. Also helpful in the treatment of Premenstrual Syndrome and Migraine Headaches. In higher doses (80-160 mg/kg) has a reciprocal stimulation effect. Does not induce muscle relaxation, drowsiness or lethargy.

Contraindications: Do not use this product if you are pregnant or lactating without first seeking advice from your physician. Do not use this product if you suffer from renal disease. Do not use this product if you have a family history or other risk factors for stroke.

Dosage and Administration: Time course of accumulation of Picamilon in the brain correlates with its blood level.

Clinical Effect In: Approximately 30 minutes.

Adverse Reactions: Picamilion produces no known allergenic, teratogenic, embryotoxic or carcinogenic effects. If you suspect that an herb or other supplement is making you sick, call the FDA's MedWatch hotline at 800-332-1088 or contact the agency via its website at http://www.fda.gov/medwatch.

Known Interactive Effects: Valerian Root may inhibit the breakdown of GABA thereby enhancing its activity in the brain. Ginseng may also potentiate the activity of GABA.

Additional Considerations:

Warnings: The information above is provided for educational purposes and may not be construed as a medical prescription or as a substitute for the advice of your physician. Do not use this product without first consulting your physician especially if you are pregnant or lactating. Be advised that some herbs and dietary supplements can cause severe allergic reactions in some individuals and may also have an adverse result in conjunction with other medications, or treatments. You should regularly consult your physician in matters regarding your health and particularly in respect to symptoms and conditions which may require diagnosis or medical attention. Reevaluate use of this product after 6 months.

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